Because they are so reactive, organometallic reagents are generally prepared just before use. Organolithium reagents are available commercially as solutions in inert solvents such as diethyl ether, tetrahydrofuran (THF), or pentane. Still, they have a short shelf life and must be handled under an inert atmosphere.
The procedure for generating either type of reagent is similar: an alkyl or aryl halide is treated with magnesium or lithium metal in a dry, inert solvent, most commonly anhydrous ether Read more in HAND WRITTEN notes of Organic Synthetic Reagent And Organo Metallics Reagents in Pdf
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